Chem hosts the field's first structured debate on 'reasoning SDLs' — Abolhasani Catalyst + five Reaction responses
Chem's August 2026 issue (Vol. 12/8) pairs Milad Abolhasani's Catalyst commentary 'When self-driving labs begin to reason' — arguing the SDL bottleneck has moved from executing experiments to deciding what science to do next — with five invited Reaction responses from leading groups: Chen/Xie/Jiang (USTC) call for experimentally grounded chemical world models; Boser/Glorius (Münster) bring synthetic-chemistry adoption realism; Fan/Liu (UCLA) demand agentic AI that explains as well as optimizes; Aspuru-Guzik/Bernales (Toronto) argue for trust infrastructure 'beyond fragile eloquence'; and Sin/Segura/Winkler/Schwaller (EPFL LIAC + Roche) frame reasoning labs as reproducible physical infrastructure. Notably, every response converges on verification and infrastructure rather than raw capability — the same month the anchor author's Nature Reviews Chemistry review recast SDLs as shared scientific infrastructure.